Gutsyl Review


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Value Rating
Customer Rating
Overall Rating 
Our research has shown that this manufacturer has created a product born from science and clinical data. We found that this was the only product to contain the exact vitamins, minerals and herbs which have been clinically proven to reduce leaky gut symptoms, support healing of the intestinal lining and balance healthy bacteria levels in the GI tract. Moreover, it includes Berberine together with BioPerine® as a trademarked blend for enhanced bioavailability and stronger microbial properties. Dosage is based on clinical studies which suggests that these guys are serious about what they do. We liked that it’s served in a vegan-friendly capsule as well as offers a 60-day money-back guarantee if you are not happy with the results. 

Why We Consider Gutsyl To Be An Effective Product

Main Benefits:

  • It contains Berberine combined with BioPerine® as a trademark blend (MicrobiSci™) to create an optimal bioavailable microbial effect to help protect the gut.
  • It contains a powerful 600 mg daily serving of L-glutamine, an essential amino acid for supporting intestinal lining repair and strengthening.
  • It contains all 4 ingredients that help protect the lining of the gut. These include Aloe Vera, Marshmallow, Slippery Elm and Licorice.        
  • It contains Turmeric and Quercetin which work synergistically with Berberine to provide the ultimate antimicrobial and anti-inflammatory support..    
  • It contains Acacia Fiber which helps support a healthy balance of bacteria in the gut with its prebiotic properties.
  • It does not contain any preservatives, artificial colorings, hormones, fillers or binders.
  • Many supportive consumer reviews from users who had experienced excellent results.
  • It does not contain any unnecessary ingredients that may dilute the efficacy of the product.
  • Its daily suggested serving is the optimal potency as recommended by doctors, for effectiveness and is supported by extensive clinical research trials and studies.
  • This manufacturer’s customer service is second to none and provides excellent support and help. Furthermore, they offer an excellent money-back guarantee if customers are not happy with the results they experience.


There are several key studies that help pinpoint the way when it comes to finding the most effective leaky gut supplement that will combat LGS symptoms and support a healthy GI tract.

These natural ingredients linked to supporting the intestinal lining to make it less permeable as well as boosting a stronger immune system and restoring regular digestive function include L-glutamine, Aloe Vera, Marshmallow and Quercetin.

First and foremost, a quality leaky gut supplement should be formulated with clinically proven ingredients that help address the root cause as well as the challenging symptoms. The trademarked blend of Berberine and BioPerine® provides a powerful antiviral effect and facilitates the absorption of the main ingredients for faster and more effective results.

Secondly, there should be at least 600 mg of L-glutamine offered per daily serving. This essential amino acid provides an extremely important role in repairing and strengthening the lining of the gut.

Thirdly, the inclusion of all 4 key ingredients that protect the gut lining, include Aloe Vera, Marshmallow, Slippery Elm and Licorice. The combination of all 4 is crucial for enhancing the function of the intestinal barrier and offering protection and repair of the intestinal lining.

Fourthly, it is essential that there be strong anti-inflammatory components such as Turmeric and Quercetin which help reduce inflammation, a common characteristic of leaky gut syndrome.

Lastly, a balanced level of bacteria is crucial for a healthy gut, so adding the prebiotic Acacia Fiber is an essential element (as opposed to adding probiotics which can be difficult to stabilize in an inflamed gut).

Many companies that enjoy a positive reputation, take advantage of their good standing with the public in order to sell cheap health supplements. It’s so distressing how easy it is, which is why it is incumbent on every consumer to do their own fact-finding on any health product they purchase.

Gutsyl contains effective ingredients to address an imbalanced GI tract as well as to enhance the functionality of the intestinal lining. What we really like is that it is made by a company that consistently uses clinical studies as a benchmark for the dosage of all their health supplements. There is also a money-back guarantee which can be claimed by speaking to their customer service agents who are real, not just bots!

Additionally, you will not find any ingredients in Gutsyl which shouldn’t be there. There are no added fillers, binders, additives or preservatives. There are so many products out there that do not fall within the realm of high standards, offering artificial alternatives and all sorts of extras inside their formulas. It is a relief to be able to recommend a company that manufactures such a unique, well-researched product.

To summarize, Gutsyl uses top-quality natural ingredients, provides awesome results, has a caring customer support team and a great price. From what we saw, without a doubt, this is an extremely good product.

Quality Assurance

Over the last few years, we understand how consumers have grown skeptical of nutritional health supplements. This simply comes down to shady companies providing useless formulas that contain unrelated and extraneous ingredients or that add fillers or binders to their products. Often, these ingredients are not pure, or have not been tested for quality and have no valid scientific explanation as to why they have been included in the formulas. Not only is this irresponsible, but often quite dangerous. Truthfully, there is absolutely no reason why anything artificial should be added. Natural and pure is best.

On many nutritional supplements, the label states that the ingredients are either ‘active’ or inactive’. In simple terms, the active ingredients are the reason you decided to purchase the product and the ones that actually bring you the results you are hoping for. When you see a long list of inactive ingredients, beware, often companies will fill their products with unhelpful and potentially dangerous junk.

That is why, for us, Gutsyl is a product that does not fall within this category. Its formula contains only natural and pure ingredients backed by numerous clinical studies and research. It offers a simple philosophy that seems to work well – offer top-quality ingredients in the most effective potency, great price options with a terrific money-back guarantee and you won’t be disappointed.

Another aspect of taking supplements that contain a large amount of inactive or unnecessary ingredients is the lack of understanding of how these chemicals may affect existing medical conditions or medications. If the ingredients are bona fide and in their natural form, side effects or negative interactions are unlikely to be experienced.

We were very happy to discover that Gutsyl is manufactured in an FDA-registered facility. What’s more, is that it is cGMP recognized and complies with the US Pharmacopeia’s standards for quality and purity. This suggests that this company takes what it does very seriously, and strives to keep its products safe, natural and effective – a mentality that we totally appreciate.


Gutsyl by Approved Science comes at an affordable price with some excellent multiple purchase deals, allowing for huge cost savings for consumers. Also, this company is staunchly against any auto-ship programs, as they can be nearly impossible to cancel.

Nowadays, consumers need to be ‘smart shoppers’, carrying out as much research as they can about what they would like to purchase, in order to avoid wasting their money. There are many options out there that charge a lot of money for inferior products that simply will not deliver the results that they promise. This is disheartening and quite frankly, a bad and dishonest practice.

Orders are shipped within 24 hours, with the exclusion of any orders placed on weekends and holidays. They are wrapped and sent in discreet packaging, with no identifying marks on the outside, unlike other companies who often have embarrassing slogans or logos. Furthermore, this company provides a 60-day risk-free money-back guarantee. If you are not 100% happy with the results, you are able to return the product and receive a full refund. That shows strong confidence in its product and we totally support that kind of guarantee.

In Conclusion

When people are searching for a high-quality product to strengthen their gut health, they often focus exclusively on digestion issues instead of tackling the root of the problem. 

Gutsyl specifically contains the optimal blend of ingredients that are clinically proven to enhance the intestinal barrier, reduce inflammation and balance bacteria levels. They include:

  • Bioavailable Berberine MicrobiSci™ for a more absorbent antimicrobial effect to enhance protection of the intestinal lining.
  • The 4 essential ingredients for added strength and protection of the lining of the gut: Aloe Vera, Marshmallow, Slippery Elm and Licorice.
  • 600 mg L-glutamine – an essential amino acid for repairing the intestinal lining.
  • Turmeric and Quercetin work synergistically with Berberine to help reduce inflammation in the gut. 
  • Acacia Fiber, a prebiotic that increases the intestinal population of anti-inflammatory bacteria.

Additionally, there are other significant elements to bear in mind, such as third-party testing and comprehensive customer reviews that give us a great indication of how the product really works.

Of all the products that we reviewed, across all parameters, none compared to Gutsyl. If you are looking for a top-quality formula backed by research and scientific data that is an effective, long-term solution to enhance the protection of your GI tract, strengthen the intestinal barrier and reduce inflammation, you would be hard pushed to find anything better than Gutsyl.

Carlyle Leaky Gut Support
Amen Leaky Gut
Ancient Nutrition Leaky Gut
Contains 600 mg L-glutamine to strengthen the abdominal surface for optimal digestion.
Contains the trademark blend BioBerberine™ with Berberine and BioPerine® to optimize absorption and protection of the gut.
Contains all 4 protective herbs: Licorice, Slippery Elm, Marshmallow and Aloe Vera to strengthen and protect the intestinal lining.
Contains Turmeric and Quercetin for optimal anti-inflammatory effect
Contains the prebiotic Acacia Fiber to balance gut flora
GMP certification
No additives, preservatives, or artificial ingredients to water down the positive effects
Money-back Guarantee

Read on to see what their happy customers are saying

“I’ve had LGS for a few years already and have lost count at how many products I’ve tried praying that the next one will be the gamechanger. Unfortunately I haven’t had much success, some helped slightly, but the relief was temporary. Since I started taking Gutsyl, almost all my symptoms have subsided. I don’t want to speak too soon, but I hope this isn’t too good to be true. I’m so relieved to finally have found something that actually works!”     – Stephanie Bond

“I’m a big fan of Approved Science, I love their products and appreciate the fact that everything they produce is based on scientific research. I ordered Gutsyl for my dad who has had a whole bout of issues related to his gut including bloating, exhaustion and cramping. This has solved all of them. Amazing product!”     – Mikey Ruiz

“This product has changed my life. Almost immediately I noticed my metabolism increase, I had more energy and didn’t have the after-meal cramps or bloating. I definitely would recommend this product.”     – Paul Dobek  

“I have to admit that I’m a big skeptic when it comes to all-natural products. However, I have been using Gutsyl for about a week now and to be honest, I don’t believe how much of a difference it has made. My mornings usually start off ok, but as the day progressed, the worse I felt and by the evening I’d collapse feeling miserable and in pain. Since taking Gutsyl, I don’t have that anymore. I have more energy, I’m not craving weird things and I feel so much better. Highly recommend.”     – Connie Murphy


“I haven’t exactly had the best metabolism during my adult life despite my nutritional eating habits. A friend of mine told me about Gutsyl and it seemed to have the ingredients that are known to help a leaky gut. It’s still quite new, but so far my bloat has gone down and I’m more regular than I’ve ever been before. I am very satisfied.”     – Annie Friedina

“This is an answer to my prayers. I’ve been getting these painful cramps in my stomach that can last for hours at a time. They’re extremely debilitating as I can hardly do anything efficient while having this pain. Unfortunately, regular painkillers don’t seem to be much help and I was very nervous about taking anything stronger. Every time I’ve gone on prescription medication I’ve had to deal with other side effects that are often worse than what I’m going through so I usually stop taking them halfway and give up. I came across Gutsyl online and decided to try it out. Fingers crossed, it’s been such a relief. I haven’t had one attack since taking it. I am so grateful.”     – Tatiyana Namiki

“I’ve had a bunch of gut issues for a while now and have been looking for a leaky gut supplement. After searching around for a while online, I decided on Gutsyl because it seemed to have all the ingredients in one bottle! I thought that was fantastic as it meant I didn’t need to buy separate bottles of each ingredient that’s known to be good for leaky gut. Happy to report that it really works, and I’ve never been quite so relieved!”     -Andrea Shina


FAQs about Gutsyl:

How does Gutsyl by Approved Science work?

The key lies in the ingredients contained within this formula – they haven’t simply been plucked from thin air so that they have a list of ingredients that looks good on the label! Each ingredient in this product is supported by clinical research and has a valid reason to be there! Its unique formula is based on clinical studies that have shown huge promise in the battle against leaky gut syndrome. By including a multifaceted approach using key ingredients to target LGS at its root, it works to protect and strengthen the intestinal lining, reduce inflammation, boost the immune system and restore normal digestive function. It has included effective ingredients such as Berberine, BioPerine®, Turmeric, Quercetin, L-glutamine and Acacia Fiber in a highly effective dose to ensure optimal effects and fast results to support a healthy GI tract.

What’s more, this product includes the 4 main ingredients that help protect and soothe the intestinal lining: Aloe Vera, Marshmallow, Slippery Elm and Licorice. This unique formula works to support the healing of the body’s protective membranes along the GI tract, aiming to reduce the amount of bacteria and toxins that may leak into the bloodstream. The great thing is that this formula is all natural which means that it is safe for long-term use.

Do all leaky gut products work in a similar way?

The short answer is no, they do not. There are many companies that just ride the trends, producing inferior products with weak formulas in the wrong proportions. Many use incorrect ingredients, fillers, binders or even worse ingredients that can affect desired results, and even be dangerous.

What should I look for in an effective formula?

  • It should contain Berberine combined with the bioavailability factor BioPerine® for a highly absorbent microbial effect that helps protect the lining of the gut.     
  • It should contain the 4 main ingredients to protect and soothe the intestinal lining: Aloe Vera, Marshmallow, Slippery Elm and Licorice.  
  • It should contain at least 600 mg of the amino acid L-glutamine to support intestinal lining repair and protection.
  • It should contain Turmeric and Quercetin which provide powerful antimicrobial benefits to help reduce inflammation.   
  • It should contain Acacia fiber which provides prebiotic properties, supporting a healthy balance of bacteria in the gut.
  • It should not contain any binders, fillers, additives, hormones, preservatives or artificial ingredients.
  • It must be 100% pure, natural and with no unnecessary ingredients that could reduce the effectiveness of the product.
  • It should be formulated using the same potency as found effective in clinical studies.

Are there any side effects noted when using this product?

Our research did not uncover any negative side effects when using this product. The ingredients that are contained within the formula of Gutsyl are all natural and pure. What’s more, they are doctor approved, so the lack of any negative effects is to be expected. That said, as with any supplement, we always recommend consulting with a doctor if you are pregnant, breastfeeding, have an existing medical condition or are taking any other medication.

What are the dosage instructions for Gutsyl?

The manufacturers of this product suggest taking 1 capsule, twice a day, before meals, with a glass of water. Some like taking the dose altogether and at once, but this manufacturer recommends taking one capsule in the morning and one in the afternoon for optimal results. As with any medication or supplement, always follow the recommended dosage instructions and do not exceed them as this may pose health risks.

How long before I can see any results?

Results will vary for each person. For some, they will see changes almost immediately, for others it may take longer. It is different for each person. Other factors that affect results can include age, diet and lifestyle so it is hard to say exactly. What you should look out for are those companies who offer a satisfaction guarantee. This suggests that they are confident that their products will deliver the desired results. After all, if you don’t get the results you were hoping for you can always return the product. Gutsyl offers a great money-back guarantee and awesome feedback on how well this product works.

What price should I expect to pay?

The cost of products varies between manufacturers. Unfortunately, many are cheap, useless supplements that have been formulated without any science-based evidence to back them up. Some of these companies are selling their products for over $100 per bottle, which is very expensive. On average, the best supplements we found are selling between the $40-$50 price range. Often, when products appear cheaper, this is indicative of low quality or a low recommended daily serving, which will not bring the results you are looking for. Be aware. Read the labels.

Which leaky gut supplement should I buy?

As each person’s experience of a product is different, it is difficult to say specifically which one is the best. That said, based on several factors, we did like Gutsyl by Approved Science. We found that from 50+ products that we looked at, Gutsyl had the best quality of ingredients, potency and strength, positive consumer feedback and the manufacturer’s customer service was excellent.

How safe is it to order over the internet?

Gutsyl is safe to be ordered over the internet. The manufacturer utilizes the latest encryption software to protect your credit card information and does not engage in shady schemes such as ‘automatic billing’ programs like many other companies do. They also deliver very efficiently and quickly, using discreet packaging.

Why should I choose Gutsyl?

We like Gutsyl for several reasons. It excels in many areas including purity of ingredients, service, satisfaction and effectiveness. Its formula is backed by clinical studies and we feel it values consumers’ health above and beyond the profit margins.

This is a great product that you can depend on. It has a well-researched formula with the right ingredients in the correct potency. And if that wasn’t enough, check out the customer reviews – they say it all. It is abundant with many happy customers singing the praises of this trustworthy product who are highly loyal to this brand. We will summarize the key benefits one more time:

  • It contains only all natural ingredients that are 100% pure and backed by clinical research.
  • It contains the trademarked blend MicrobiSci™ which combines Berberine together with the bioavailability factor BioPerine® for enhanced protection of the gut and faster absorption.
  • It contains the 4 main ingredients to protect and soothe the lining of the gut: Aloe Vera, Marshmallow, Slippery Elm and Licorice.
  • It contains 600 mg L-glutamine per daily serving to enhance repair of the intestinal lining.
  • It contains Turmeric and Quercetin which work synergistically with Berberine to provide powerful antimicrobial  benefits to reduce inflammation.
  • It contains Acacia fiber which provides prebiotic properties, supporting a healthy balance of bacteria in the gut.
  • It offers a recommended daily serving of 2 easy to swallow capsules. For best results, the manufacturer suggests that individuals take one in the morning and one in the afternoon before meals with a glass of water.
  • Its formula does not contain any synthetic additives, hormones, preservatives, binders, fillers or other unnecessary ingredients.
  • Its lab is FDA and cGMP recognized.
  • Its products comply with the standards for quality and purity outlined by the U.S. Pharmacopeia
  • This product is well priced and falls below average when compared to other similar products. The manufacturer of Gutsyl also provides some great discounts for multiple purchases, which can save consumers a lot of money.
  • Our research showed that the company is trustworthy, reliable, transparent and has integrity and a great reputation in the industry.
  • The manufacturer of Gutsyl offers a great 60-day money-back guarantee which can be utilized, no questions asked if you are not happy with the results. This shows that the manufacturer has a strong confidence in its products.

The Bottom Line

At the end of the day, consumers have so many options when choosing a health supplement. We are constantly being bombarded with commercials, advertisements and messages about so many different products, for varying health issues that it is beyond confusing which ones are the real deal and which ones are a waste of time. Leaky gut supplements are no exception, with many companies simply trying to cash in on the latest health trends and pushing their products on unwilling consumers.

We like Gutsyl because we feel that this company is different. It is in it for the long haul. It has researched its ingredients well and produced its formula using only pure natural elements with a lot of clinical data to back them up. The manufacturer of Gutsyl offers what more companies should – an effective, affordable product supported by a real concern for the health of their customers. As an added bonus, Gutsyl has many happy testimonials to support our belief that this is a great product and a great company.   

What You’ll Discover:

Which Leaky Gut Product is the BEST BUY and comes with a great GUARANTEE!
Which formula and ingredients are the most EFFECTIVE and work the fastest?
How NOT to get ripped off! BE AWARE of poor quality and cheap products.

Top 6 Items to Consider:

  1. Ingredients
  2. Cost Per Serving
  3. Product’s Testing Results
  4. Company’s Reputation
  5. Consumer Reviews
  6. Return Policy & Satisfaction Guarantee

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